Welch Unique Patented Technology
During the packing and purification process, the packing materials will bear great mechanical pressure, so the mechanical strength requirements of the packing materials used for preparation are usualy higher than those used for analysis. The mechanical strength of packing materials is a very important quality index, which affects the lifetime of packing materials. When packing frequently, packing materials should be very stable, or it will cause packing materials broken, which will inevitably lead to column pressure increase, column efficiency decrease and bad column performance. ln order to extend the life of the packing materials, high mechanical strength materials and strong bonding technology are required, thereby improving the customer's production efficiency and reducing the customer's cost in purifcation.
Ultra-Pure(purity > 99.999%) spherical and totally porous silica is adopted to ensure high separation column efficiency.
A uniform distribution of particle and pore sizes leads to efficient separation and allows for a greater sample loading capacity.
Fine particles can increase plate numbers and resolution, but at the same time it will cause diffculties in column packing (it requires higher operating pressure); The packing materials with narrow particle size distribution is easy to be packed evenly so as to obtain a tighter and more stable column bed, reduce the eddy current diffusion coeffcient and improve the column efficiency. Narrow pore size distribution can increase the effective surface area and increase the loading amount.Therefore the uriform distribution of particle size and pore size is the guarantee of good separation effect and large sample loading.
Ultra low metal content
Heavy metal content is an important criterion in the evaluation of packing materials. Lower the content of heavy metals, lower the non-specifc adsorption of the analyte, and more symmetry the peak shape. Welch selects the extremely low heavy metal content silica gel(content below 1ppm, certifed by a third-party testina organization) to guarantee the quality of the packing materials from the raw materials source.
Good lot-to-lot reproducibility
The chemical and mechanical stablity, pore structure and specifc surface area of packing materials are highly reproducible between batches to ensure a long-term, continuous and stable purifcation production process.
pH stability
XB-C18 was tested with different brands of packing materials under extreme conditions of pH 1.3 and 10. The test results are shown in the following figure:
Brand: Ultisil
Phase: HILIC-NH2
Particle Size: 40-70μm
Pore Size: 100Å
USP Classification:
Separation Mode:
pH Range:
Surface Area:
Carbon Load:
Max.Pressure:
Endcapped:
Max.Temp.:
Particle Shape: Spherical
Welch Unique Patented Technology
During the packing and purification process, the packing materials will bear great mechanical pressure, so the mechanical strength requirements of the packing materials used for preparation are usualy higher than those used for analysis. The mechanical strength of packing materials is a very important quality index, which affects the lifetime of packing materials. When packing frequently, packing materials should be very stable, or it will cause packing materials broken, which will inevitably lead to column pressure increase, column efficiency decrease and bad column performance. ln order to extend the life of the packing materials, high mechanical strength materials and strong bonding technology are required, thereby improving the customer's production efficiency and reducing the customer's cost in purifcation.
Ultra-Pure(purity > 99.999%) spherical and totally porous silica is adopted to ensure high separation column efficiency.
A uniform distribution of particle and pore sizes leads to efficient separation and allows for a greater sample loading capacity.
Fine particles can increase plate numbers and resolution, but at the same time it will cause diffculties in column packing (it requires higher operating pressure); The packing materials with narrow particle size distribution is easy to be packed evenly so as to obtain a tighter and more stable column bed, reduce the eddy current diffusion coeffcient and improve the column efficiency. Narrow pore size distribution can increase the effective surface area and increase the loading amount.Therefore the uriform distribution of particle size and pore size is the guarantee of good separation effect and large sample loading.
Ultra low metal content
Heavy metal content is an important criterion in the evaluation of packing materials. Lower the content of heavy metals, lower the non-specifc adsorption of the analyte, and more symmetry the peak shape. Welch selects the extremely low heavy metal content silica gel(content below 1ppm, certifed by a third-party testina organization) to guarantee the quality of the packing materials from the raw materials source.
Good lot-to-lot reproducibility
The chemical and mechanical stablity, pore structure and specifc surface area of packing materials are highly reproducible between batches to ensure a long-term, continuous and stable purifcation production process.
pH stability
XB-C18 was tested with different brands of packing materials under extreme conditions of pH 1.3 and 10. The test results are shown in the following figure:
Brand: Ultisil
Phase: HILIC-NH2
Particle Size: 40-70μm
Pore Size: 100Å
USP Classification:
Separation Mode:
pH Range:
Surface Area:
Carbon Load:
Max.Pressure:
Endcapped:
Max.Temp.:
Particle Shape: Spherical