Welch Unique Patented Technology
During packing and separation/purification processes, the packing material undergoes significant mechanical pressure. Therefore, the mechanical strength requirements for preparative packing materials are usually higher than those for analytical use. Mechanical strength is an extremely important quality indicator that directly impacts the lifespan of the packing material and the production process. Frequent column packing requires highly stable materials; insufficient mechanical strength can cause particle breakage, leading to increased column pressure, decreased column efficiency, and compromised performance. High mechanical strength combined with robust bonding technology extends the packing material’s lifespan, ultimately enhancing production efficiency and reducing separation and purification costs for customers.
Ultra-High Purity Fully Porous Spherical Silica (Purity >99.999%): Ensuring High Separation Efficiency
Uniform Particle Size and Pore Size Distribution for Optimal Separation Efficiency and Higher Sample Load
Finer particles increase theoretical plates and resolution but complicate column packing, require higher operating pressure, and lead to higher column pressure. Packing materials with a narrow particle size distribution facilitate uniform packing, resulting in a tighter and more stable column bed, reducing eddy diffusion and improving column efficiency. A narrow pore size distribution increases the effective surface area, thereby enhancing sample load capacity. Thus, uniform particle and pore size distribution are crucial for achieving excellent separation efficiency and higher sample load.
Ultra-Low Metal Content
Metal content is a critical factor in evaluating packing material quality. Low metal content minimizes non-specific adsorption of analytes, ensuring symmetrical peak shapes. Welch Materials’ selected silica packing materials have extremely low metal content, all below 1 ppm, as verified by third-party testing agencies. By controlling metal content at the source, we ensure the highest packing material quality.
Excellent Batch-to-Batch Reproducibility
Each batch of packing materials exhibits high chemical and mechanical stability, consistent pore structure, and specific surface area, ensuring long-term, continuous, and stable separation and purification processes.
pH stability
XB-C18 and packing materials from other brands were tested under extreme pH conditions (pH=1.3 and pH=10), with the experimental results shown below.
Brand: Ultisil
Phase: LP-C18
Particle Size: 10μm
Pore Size: 120Å
USP Classification:
Separation Mode:
pH Range:
Surface Area:
Carbon Load:
Max.Pressure:
Endcapped:
Max.Temp.:
Particle Shape: Spherical
Welch Unique Patented Technology
During packing and separation/purification processes, the packing material undergoes significant mechanical pressure. Therefore, the mechanical strength requirements for preparative packing materials are usually higher than those for analytical use. Mechanical strength is an extremely important quality indicator that directly impacts the lifespan of the packing material and the production process. Frequent column packing requires highly stable materials; insufficient mechanical strength can cause particle breakage, leading to increased column pressure, decreased column efficiency, and compromised performance. High mechanical strength combined with robust bonding technology extends the packing material’s lifespan, ultimately enhancing production efficiency and reducing separation and purification costs for customers.
Ultra-High Purity Fully Porous Spherical Silica (Purity >99.999%): Ensuring High Separation Efficiency
Uniform Particle Size and Pore Size Distribution for Optimal Separation Efficiency and Higher Sample Load
Finer particles increase theoretical plates and resolution but complicate column packing, require higher operating pressure, and lead to higher column pressure. Packing materials with a narrow particle size distribution facilitate uniform packing, resulting in a tighter and more stable column bed, reducing eddy diffusion and improving column efficiency. A narrow pore size distribution increases the effective surface area, thereby enhancing sample load capacity. Thus, uniform particle and pore size distribution are crucial for achieving excellent separation efficiency and higher sample load.
Ultra-Low Metal Content
Metal content is a critical factor in evaluating packing material quality. Low metal content minimizes non-specific adsorption of analytes, ensuring symmetrical peak shapes. Welch Materials’ selected silica packing materials have extremely low metal content, all below 1 ppm, as verified by third-party testing agencies. By controlling metal content at the source, we ensure the highest packing material quality.
Excellent Batch-to-Batch Reproducibility
Each batch of packing materials exhibits high chemical and mechanical stability, consistent pore structure, and specific surface area, ensuring long-term, continuous, and stable separation and purification processes.
pH stability
XB-C18 and packing materials from other brands were tested under extreme pH conditions (pH=1.3 and pH=10), with the experimental results shown below.
Brand: Ultisil
Phase: LP-C18
Particle Size: 10μm
Pore Size: 120Å
USP Classification:
Separation Mode:
pH Range:
Surface Area:
Carbon Load:
Max.Pressure:
Endcapped:
Max.Temp.:
Particle Shape: Spherical